Upstream is a comprehensive curriculum built from the wisdom of 91 world-class clinicians — designed to teach you everything there is to know about gut health, so you can finally fix what's actually wrong.
Or — no test required.
The gut health industry sells products. It doesn't teach you the science. Without understanding the system, you're guessing — and guessing is expensive.
Probiotics, prebiotics, enzymes — all useful, but only if you know what your microbiome actually needs. Without testing, you're supplementing blind.
Bloating is a symptom. Brain fog is a symptom. The root cause is upstream — often in the oral microbiome, the gut barrier, or the HPA axis. Most practitioners never look there.
Even if you've had testing done, lab results without clinical context are just numbers. Upstream teaches you to read your own biology.
Upstream combines clinical-grade testing with a 52-week curriculum built from the world's leading functional medicine research. Every lesson traces your symptoms back to their biological source — so you understand not just what is happening, but why, and exactly what to do about it.
91
World-class clinicians
126+
Modules of curriculum
365
Daily lessons
3
Clinical test panels
Every lesson draws from the clinical wisdom of physicians, researchers, and practitioners at the frontier of functional gut medicine.
Dr. Mark Hyman
Functional Medicine Pioneer
Gut-Brain AxisDr. Zach Bush
Microbiome Researcher
Soil & Human MicrobiomeDr. Tom O'Bryan
Autoimmunity Expert
Leaky Gut & GlutenDr. Robynne Chutkan
Gastroenterologist
Microbiome RestorationDr. Steven Gundry
Cardiac Surgeon & Author
Lectins & Gut LiningDr. Emeran Mayer
Gut-Brain Researcher
Mind-Gut Connection+ 85 more clinicians across gastroenterology, immunology, neurology, and functional medicine
Thousands of students have used Upstream to resolve chronic symptoms their doctors couldn't explain.
"My bowels have returned to normal after 10 years of dealing with diarrhea. Ten years! I can't believe how much this program has changed my life in just two months. I finally feel like I have my health back."
— Carie O.
✓ 10 years of diarrhea resolved in 2 months
Start with the FIT 22 — your first data point. Your results are what earn a review call with our team. No experience required.
KBMO FIT 22 Gut Test Kit
$199Food sensitivities + gut permeability. Your first data point — real clinical data that maps directly to your protocol.
Orobiome Oral Microbiome Test
$399Map the upstream source — the oral pathogens driving gut dysfunction, cardiovascular risk, and systemic inflammation.
Explore Testing Tier
$1,450The complete picture: Orobiome + KBMO FIT 176 + GI-MAP. Everything your functional medicine team needs to build a precision protocol.
Answer 5 quick questions and we'll match you to the exact Vitaboom supplement protocol our clinical team recommends for your symptoms — 90 seconds, no email required.
Already know what you need?
Join thousands of students learning the science of gut health from the world's leading functional medicine clinicians — 20 minutes a day, one lesson at a time.
Questions? Start with the KBMO FIT 22 Gut Test Kit — your results are what open the door to a team call.