Functional Medicine · Root Cause · Dr. Pedram Shojai

Every symptom has a source.
We find it upstream.

Three tributaries. One river. The platform that connects your gut, your sleep, and your toxic burden — and gives you a clear path out.

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Three tributaries · One river

Where are you feeling it?

Most people have one dominant symptom cluster. Find yours below. Each path starts with a single test at $399 and leads to the full picture.

The Gut Tributary

You're not intolerant to food.

Your gut lining is intolerant to what's been done to it.

Sound familiar?

  • Bloating after meals
  • Food reactions multiplying
  • Fatigue after eating
  • Diagnosed with IBS
The Sleep Tributary

You don't have a sleep problem.

You have a gut-adrenal problem that shows up at 2 AM.

Sound familiar?

  • Waking at 2–4 AM
  • Can't get back to sleep
  • Exhausted by 10 AM
  • Melatonin doesn't work
The Detox Tributary

Your brain fog is not stress.

It's chemistry. And we can measure it.

Sound familiar?

  • Brain fog nobody explains
  • Chemical sensitivities
  • Mystery symptoms
  • Diagnosed with fibromyalgia or CFS
The River

All three paths lead here.

The Upstream platform combines your lab data, the world's leading functional medicine curriculum, and a personalized protocol — so you understand not just what is wrong, but exactly what to do about it.

126+
Curriculum modules
Built from the world's leading research
91
Expert clinicians
Pimentel, Fasano, Mayer, Perlmutter & more
3
Clinical test panels
Gut · Sleep · Detox

Built by Dr. Pedram Shojai

Pre-med. Became a monk. Earned a doctorate in Oriental medicine. Spent 20 years at the intersection of ancient wisdom and modern functional medicine. Built this platform because the answers exist — they just aren't in the places most people look.